The only plausible use case I could come up with is if a game company earnestly and legitimately wants to allow but outsource a real-money marketplace. As a cost saving measure for their own benefit.

If e.g. Diablo allowed legendaries to be owned based on an NFT, offered zero opinion on its legitimacy, said "whelp nothing we can do" to customers losing their items to scams or accidents, and didn't add any smart contract taxation or other shenanigans, it could work.

It wouldn't improve the game for the players, but it would finally be a legitimate use case that improved something for someone without being a pixellated ponzi scheme.