Switching off notifications has been the best thing for me, it's so much easier to not get dragged down that path when you only know if someone has replied if you actively check, which is generally a lot easier to not do, than ignoring notifications is!
I will give reddit credit for one thing - being able to control notifications on individual posts (didn't have to be your own), and even individual comments was a great little feature, but in an all or nothing scenario, nothing has proven to be the better option.