this post was submitted on 31 Mar 2024
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[–] [email protected] 78 points 8 months ago* (last edited 8 months ago) (3 children)

Just so everyone knows, you can't really transplant dead organs (at least not as safely or with the success of live organs).

They can only use your organs if you die in a hospital setting. They will keep pumping blood to your organs after you die to keep them "fresh" and "alive."

Post-death organ transfer exists but is way more risky than an organ that was recently in a living, functioning body.

So if you've ever considered it, keep in mind that you have to die at a hospital for it to happen, and even then, they're still technically forcing your body to be alive to keep these organs alive.

Source: Friend who lost his leg to amputation during a COVID-coma. They didn't think he would make it. He woke up in the donor ward. EDIT: Just to be clear, this happened during peak COVID before the vaccines when bodies were just piling up everywhere. I don't think a coma patient waking up in the donor ward is a normal thing, I think it happened because COVID was a fucked up situation and people were overwhelmed.

[–] [email protected] 20 points 8 months ago (1 children)

What does it even look like when you wake up in a donor ward? Was he a write-off and the doctors were just like 'oh shit, he's awake'? Do non-donors simply get disposed of instead of being brought there?

[–] [email protected] 19 points 8 months ago* (last edited 8 months ago) (1 children)

He's older and it's been tough to get explicit details from him, but yeah it sounds like because it was during COVID and beds for bodies were so scarce, on top of the fact that they didn't have high hopes for him surviving (so many people his age with COVID just never made it), that they were keeping in there for simplicity's sake. Anyway, it spurred me to begin looking into organ donation actually functions, and I mean, it makes sense, I just hadn't really thought about it before that you technically have to have your body being kept alive to be able to donate the organs. A rotting organ probably isn't very useful. That's why it usually happens with terminal patients where the outcome is 100% they are gonna die. During COVID, with bodies piling up, and lack of open beds in hospitals, it at least makes sense to me that he would have ended up there, in case he didn't wake up. It was pandemonium, at the time. Sadly, it seems to have kind of messed with his head to wake up in that situation, he's a lot less trustful of doctors now.

[–] [email protected] 10 points 8 months ago (1 children)

If I'd walk up from coma with one leg less, I might lose my trust in doctors too...

[–] [email protected] 13 points 8 months ago (2 children)

It’s not the leg amputation, I believe, they considered him β€œas good as dead” when he went into coma. He knew he was getting an amputation. What he didn’t expect was that he would wake up to a nightmare of being prepped for his other organs to be removed.

[–] [email protected] 2 points 8 months ago

Damn that is a nightmare. That's not just trust issues, that's a legitimate traumatic event. That is trauma.

[–] [email protected] 1 points 8 months ago

Sorry, I misunderstood your post.

[–] [email protected] 13 points 8 months ago (3 children)

I worked as a transplant coordinator for a few years, and you're mostly right, but there qre a few points I would clarify.

Dead is dead. All transplants are post death.

All of your organs need oxygen to keep functioning. When they don't have oxygen, the cells die and the organ stops working, but you can be dead and have functioning organs.

When your brain is deprived of oxygen, the neurons stop firing and you're gone. Dead is the irreversible cessation of brain activity. Sometimes organs can heal, but once your brain is gone, you're dead.

Sometimes that happens because your heart stops beating. The muscle in your heart can also die, and it will stop pumping blood. This heart failure deprives your brain of blood, and then you die. When your heart is failing, you can stimulate the heart to keep beating and continue to live. But if your heart stops beating and you die, that is called a cardiovascular death.

You may also lose oxygen due to a failure of the lungs. Lungs put oxygen in your blood, and if your lungs fail, you don't get oxygen to your brain and you die. This could be related to the lungs, the vasculature between the heart and lungs, or any combination of the three.

The liver and the kidneys work to filter the blood. If either of these fail, your blood can become toxic and poison your heart, your lungs, and/or your brain. The liver and kidneys also need oxygen to live, so if your heart stops beating or your lungs stop providing oxygen, then they will begin to die at the same time as your heart.

Like your organs, your muscles, skin, and nerves also need oxygen to live, and if you have trouble getting oxygen to your peripheral systems, your limbs can begin to die and become necrotic. Necrotic tissue creates a feedback loop of decay in your blood stream, and often requires amputation.

Covid affects both the lungs and the heart. Lung damage reduces oxygen in the blood, and heart failure reduces the flow of blood to the extremities.

Now, in the event of a traumatic brain injury, like a motorcycle accident, the brain can be killed before the other organs begin to die. The heart has a special mechanism that allows it to continue beating without input from the brain. These are ideal circumstances for organ donation, because the donor has died but their transplantable organs are in good condition.

It might be different in other countries, but in the USA, there is a network of transplant professionals that work together to procure and distribute transplants. They work with the hospitals to identify potential donors and talk to the families about donation options.

The hospital would call the local organ procurement organization every time any patient had a traumatic brain injury, even before they died. Patients would continue to receive treatment in the same area of the hospital by the same doctors and nurses. There is no "donor ward" and the only difference in treatment is that additional efforts will be made to keep the transplantable organs alive.

The patient's doctor wants to keep their brain alive along with everything else, and they only stop trying when it becomes impossible to succeed.

So, while I'm sure that your friend really did experience the loss of a limb, and I'm certain the OPO had dispatched a transplant coordinator to evaluate your friend for donation, there's no way the family was approached for possible donation without a dire prognosis (or maybe they asked). The approach would have been in the same conversation where they discuss withdrawing care because there is no hope.

The doctors and the family may have mentioned that they had discussed donation to demonstrate how dire the situation seemed, and how close to death your friend was, but they would not have altered his care at all or moved him to a special section for donors.

[–] [email protected] 6 points 8 months ago* (last edited 8 months ago) (1 children)

His parents both died of COVID while he was in the coma. While I'm sure you're very correct in everything you're saying, he was basically a "ward of the State" at that point, considering his "family" was now deceased. He was already on SSI when this happened, and his parents dying kind of fucked up a lot of things because suddenly he had an inheritance and Social Security cut off his SSI funding because now he had technically too much money to qualify.

[–] [email protected] 8 points 8 months ago

That's fucked up. It must have been horrible to wake up to all of that.

As a ward of the state, he would have been assigned a case worker who would have been in charge of his care and end of life decisions. The TCs would have still tried to find next of kin or any family that could provide consent (and a medical and social history). Besides the legal implications, there's also a PR consideration. Transplant organizations are keenly aware of the public perception, and they will go to any lengths to avoid the narrative that the state killed someone to steal their organs. If there was a third cousin in Germany, they would have gotten a phone call before decisions were made.

[–] [email protected] 5 points 8 months ago (1 children)

ICU PA here who frequently deals with all of this. Amazing information, thank you.

Would just like to add to the conversation that tissue like corneas can still be donated in even circumstances where other more sensitive organs are nonviable. Please correct me if I'm wrong!

[–] [email protected] 6 points 8 months ago (1 children)

You're right, same with bone and skin.

[–] [email protected] 4 points 8 months ago

Hey that's something! Maybe all this moisturising will pay off

[–] [email protected] 3 points 8 months ago

Now, in the event of a traumatic brain injury, like a motorcycle accident, the brain can be killed before the other organs begin to die. The heart has a special mechanism that allows it to continue beating without input from the brain. These are ideal circumstances for organ donation, because the donor has died but their transplantable organs are in good condition.

This is why they call them donor-cycles! Also why early summer is peak donation time. Yay!

[–] [email protected] 13 points 8 months ago* (last edited 8 months ago) (1 children)

Sorry to hear about your friend.

I don't think knowing this fact should discourage anyone from choosing to be a donor, though. It just means that yeah, it's unlikely that you'll be in a position where they can use your organs when you die, but it doesn't hurt to be put on the list just in case.

Iirc, I think a lot of organ donations end up being from people in motor vehicle accidents.

I did get to see one case where they harvested the person's bones instead of their organs. Didn't even know that was a thing. I'm not sure if they died in a hospital setting or not. Might be you get more time to harvest bones as opposed to organs?

[–] [email protected] 10 points 8 months ago (1 children)

Oh yeah, I hope I don't dissuade anyone. I just hadn't ever really deeply thought about it before, despite being a registered organ donor. It's an interesting conundrum to me, because you need fresh, live organs, but you can't reasonably take those from fresh, live people most of the time, so you need people who are literally on death's door, who aren't going to make it, to have their bodies kept artificially alive for the purpose of organ transfer. COVID was just a fucked up situation all around with not enough beds and so many people dying. My friend had a rough experience, but it's hardly the norm.

[–] [email protected] 6 points 8 months ago (1 children)

Yeah I'm so glad that we're not still in that disaster. I mean, I know COVID is still out there, but thankfully in much smaller numbers and we have a much greater capacity to treat it nowadays... especially without hospitals being overwhelmed.

I've seen cases where patients actually ended up getting lung transplants in an attempt to save them with COVID. I handled the diseased lungs and they were so bizarre looking.

[–] [email protected] 4 points 8 months ago (1 children)

Wow, I didn't know about the covid lung transplants. If you don't mind me asking, could you describe the covid lungs/how they looked different to healthy lungs? Just morbidly curious

[–] [email protected] 2 points 8 months ago (1 children)

Sure thing. It's been a while and I've only seen a few, but I'll do my best.

So normal lungs are puffy enough, and smooth and glistening on the outside. On the inside, they resemble a kitchen sponge. They are soft and pliable, and able to easily contract and expand to inhale and exhale air.

In these COVID lungs, the outside was very ragged and shaggy. They were distorted with a lot of contracted areas. When you cut into it, there was some residual spongy areas, but a lot of it was white, firm, and solid. Think of how you might get a gnarly scar on your arm from a bit cut. Except instead of just being a single scar, almost the entirely of the lungs are scarred and firm. They aren't able to contract and expand easily anymore because of how firm and rigid they've become. And because they no longer have the spongy architecture, it means many of the airspaces are lost and there is far less areas for potential gas exchange.

So I'm not positive, but I'm fairly sure these COVID lung transplant attempts are primarily performed on younger patients after their body was able to clear the virus. It's just that in these individuals, although they no longer had COVID, the resulting scar tissue absolutely destroyed their lungs. It doesn't happen in every case thankfully...or even most cases, but when it does it's a bit scary.

I remember one of my cases being a young pregnant woman who had to be put on an ECMO machine (artificially oxygenates the blood when your heart and/or lungs cannot). I don't know whatever came of her, but I hoped she was able to go on and lead a relatively normal life.

You can read a bit more about this sort of thing here: https://en.wikipedia.org/wiki/Interstitial_lung_disease

[–] [email protected] 2 points 8 months ago (1 children)

Wow, that was really interesting. Thanks for typing that up

[–] [email protected] 1 points 8 months ago

No problem. I get to see some nat things from time to time.