I learned a long time ago to take control of my life, decide what's important to me and what's not, and plan things out including time to relax/vacation/disconnect (by which I mean everything from taking an hour break at lunchtime, to deciding to go out for a hike on Sunday, to taking a three-week snowboarding trip). The biggest problem will always be others trying to manipulate you to do things that they want you to do; you have to learn to be direct and say "no". You also have to learn to deal with "doing what is expected of you" / "doing what is socially acceptable" / "keeping up appearances"; you have to decide what you're going to do and not let these things drag you down.
Sorry... that isn't really advice, or five top-tips for organizing your schedule, or how-to-deal-with-demanding-people... its just a bit of a harsh statement to f*ckin' take control of your life and be confident in your decisions.