this post was submitted on 19 May 2024
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[–] [email protected] 2 points 5 months ago (3 children)

I understand the motivation behind this opinion and would like to see testing of beauty products on animals outlawed. But pigs with lipstick is not really what you take the most issues with, is it? It's about giving rabbits cancer so we can test new cancer drugs on them. Assuming we make that illegal, how do you propose new cancer treatments should be tested?

[–] [email protected] 1 points 5 months ago (2 children)

Why would it be ok to test on non-human animals but not on humans?

[–] [email protected] 1 points 5 months ago (2 children)

Both occurr.

There are experimental medication trials with volunteer human subjects, often people in a situation where they have nothing to lose and whatever small contribute they may give to advance knowledge on a given field may very well be their last (or only) act of compassion towards others.

Make-up and so called beauty products can and should be tested on humans alone. But medications and other alike present too much of an unknown outcome to test outright on humans. Too many could die before any good data could be gathered to improve whatever is being developed, which would render most research undoable.

Animal testing is, as we stand, a necessary evil we must all carry with us. Let us hope we find a way to end this in a very near future.

[–] [email protected] 1 points 5 months ago* (last edited 5 months ago) (2 children)

If humans would treat nature and themself better we wouldn't need any "beauty" products or even any medication in the first place. Just to artificially look "better" or live longer?

Everything that happens to us, is because our own selfishness ego to think we are the "alpha" product who owns everything, while we are just dumpshit animals with no respect for nothing.

You wan't to test some product? Go test it on criminals and leave those poor animals alone. But no, testing on non volunteer human is not ethical correct??

Oh yeah that's where we draw the line.

[–] [email protected] 1 points 5 months ago

If humans would treat nature and themself better we wouldn't need any "beauty" products or even any medication in the first place.

How?

Just to artificially look "better" or live longer?

Vanity is a flaw, I agree. Age is not something to be ashamed of.

Everything that happens to us, is because our own selfishness ego to think we are the "alpha" product who owns everything, while we are just dumpshit animals with no respect for nothing.

Hubris is to blame for many mistakes people do but no animal or living being has respect for anything else besides the immediate survival. Animals will destroy others habitats, food, brood, etc, because the others impede their way.

You wan't to test some product? Go test it on criminals or orther deranged humans and leave those poor animals alone. But no, testing on non volunteer human is not ethical correct??

Why criminals? Why not simply use any individual. If consent is the crux of the matter, let's go that way full force.

Oh yeah that's were we draw the line.

Yes. It's called self preservation. All life is to be protected until there is no other option than to end it and carry the burden for such choice. We don't live in Dante's Inferno.

[–] [email protected] 0 points 5 months ago (1 children)

Assuming a young adult develops, idk breast cancer or something. Your sister or your daughter or you maybe. Should we treat it?
If we don't they'll die.
But careful, it will cost a hundred rats and a few rabbits their lives.

[–] [email protected] 0 points 5 months ago* (last edited 5 months ago) (1 children)

I will just answer that question even though it doesn't make sense because we are in this shit together...

We wouldn't have to treat cancer if we haven't been so stupid in the past... Back to the roots with less plutonium, uranium, 4G, 5G, wifi 4,5,6, processed food, poluted water... You name it !

Maybe it's time to find a solution for the root cause and not a solution for the symptoms...

That's the difference !

[–] [email protected] 1 points 5 months ago

Reducing carcinogens would reduce the cancer rate a bit. Banning smoking completely would probably be the best first step. But most of the items on your list are either already heavily regulated (radioactive elements, food and water) or don't actually have any impact on cancer rates (the list of radio spectrum parts)

Also you're lying to yourself if you truly think that getting rid of modern advances all together would eliminate cancer. Cells sometimes mutate when dividing and in a fraction of those cases it leads to cancer. That's life. There will always be a chance of that.

[–] [email protected] 0 points 5 months ago

The animals didn't consent either and will also die.

[–] [email protected] -1 points 5 months ago (1 children)

Do you participate in modern medicine? Do you have any vaccinations or taken any antibiotics? Animal testing makes it possible. What alternative do you propose?

[–] [email protected] 1 points 5 months ago (1 children)

Notice how you didn't answer the question.

[–] [email protected] 0 points 5 months ago (4 children)

I did, but let me be more explicit for you. Animal testing is necessary because it makes modern medicine possible.

Now, if we outlaw animal testing, what alternative should we take? That's three timese now. You haven't been able to give an answer yet.

[–] [email protected] 1 points 5 months ago (2 children)

Maybe there currently aren't alternatives specifically because they aren't needed as in why develop alternatives when the status quo isn't challenged and testing on animals is the norm?

[–] [email protected] 0 points 5 months ago* (last edited 5 months ago)

Meat eaters will never challenge the status quo.

Edit: As usual, those friendly and loving fellas have nothing but downvotes. Keep on killing them!

[–] [email protected] -1 points 5 months ago

No one likes animal trials, most of all the researchers themselves who work with the animals. For example researchers cannot take any vacation during the trial. In fact someone needs to be in the lab at least once a day, including Sundays and public holidays.

Also animal trials are expensive.

Research on alternatives is progressing. It's not like there is a big conspiracy of sociopaths that get off on animal suffering and want to keep the status quo because of that. It's simply really really really hard to simulate a body to the necessary level.

[–] [email protected] 1 points 5 months ago (1 children)

That isn't an answer to the question:

Why would it be ok to test on non-human animals but not on humans?

[–] [email protected] -2 points 5 months ago (2 children)

Because humans are more valuable. If you had to choose between saving one human, and one hundred rats, which would you choose? We test on rats until we deem it safe and ethical enough to progress to testing on humans.

[–] [email protected] 1 points 5 months ago

What is it about humans that makes them more valuable? And valuable in what way?

[–] [email protected] 1 points 5 months ago* (last edited 5 months ago)

That doesn't make the lives of animals worthless. And they are treated as less than worthless.

[–] [email protected] 1 points 1 week ago

They're a troll, suggesting direct testing on humans, never even occurred to them how messed up that would be.

[–] [email protected] 1 points 5 months ago

Consensually harvested Lab-grown human body parts.

[–] [email protected] -1 points 5 months ago (2 children)

It's in part an issue of consent. The animals can't consent to what's being done to them, so to force testing on them is fucked up.

The alternative is voluntary human testing. In an ideal world, we would have good models and simulations to filter out the riskiest drugs (these kinds of models aren't being prioritized in part because people are fine with animal abuse), and then people would volunteer to be parts of trials.

In our current world, we could pay people to take part in trials. We already do this at least in the US, but usually after initial rounds of animal testing. So increase the payout dramatically for the initial rounds which are much riskier. We already pay people to do other forms of risky jobs, why should this be different?

You know who else can help test cancer treatments? Humans with cancer who want to try them.

[–] [email protected] 4 points 5 months ago* (last edited 5 months ago)

In our current world, we could pay people to take part in trials.

The majority of people I know today regularly participating in cosmetic trials are desperate for a bit of cash. That would just make imporvished desperate people go to get cancer in exchange for temporary survival through money, we would be treating poor people like the animals we wanted to save instead.

Not much different than how people are accepting of terrible jobs for terrible pay because theres no other choice.

[–] [email protected] 1 points 5 months ago (1 children)

Models and simulations are already used to develop new drugs. But the tech is simply not there yet to rely on that exclusively.

Voluntary human trials are already a requirement as well. The problem is that there are not many cancer patients that are beyond saving and still in the condition to take part in such trials.

I don't know how it is in other countries, but in Germany it's illegal to pay someone to take part in clinical trials. You are paid money to compensate you for your time and travel costs, but it's not proper pay. And there is very good reason for that. If you make medical trials a viable income, you will inevitably get poor people to take part in them. You may consider that more ethical than animal trials. I do not.
The comparison with risky jobs is not valid, because we do our best to make those jobs safer. A trial for a new drug inevitably involves getting infected with the disease the drug is supposed to cure.

[–] [email protected] 0 points 5 months ago (1 children)

We should make it easier for cancer patients to opt-in to trials.

I do consider that more ethical, however it's still far from ideal. We can do our best to make medical trials safer too, not sure why it would be different

[–] [email protected] 0 points 5 months ago (1 children)

If you're a suitable candidate I'm pretty sure they already explicitly ask you if you'd like to participate.

I'm curious what methods you suggest to make medical trials more safe. In e.g. construction we can regulate personal protection equipment and mandate machines to do the heavy lifting instead of the workers. We can mandate more time off and corporate fitness programs to keep the people healthy. But how would you make a safer clinical trial?

[–] [email protected] 0 points 5 months ago (1 children)

Better non-animal pre trial tests (this is a broad category of things), full health care such that any side effects will be cared for and they'll be compensated for accordingly, better information sharing so people can give fully informed consent.

those are the main things that come to mind off the top of my head, I'm sure there are other things that could go into it too

[–] [email protected] 0 points 5 months ago* (last edited 5 months ago) (1 children)

Oh, I had hoped for some proper thoughts on the matter. The first suggestion is too vague and the other two are already the status quo. In fact I have heard (anecdotally) someone got treated for something that, with 99.9% certainty, was unrelated to the clinical trial they, were participating in. But it occurred during the trial, so their health care costs were covered in full by the clinical trial. And if you ever witness that participants of a clinical trial were not fully informed you should report it. The ethics committee and lawmakers take that extremely seriously.

Edit: to better explain my previous point about safety. When we talk about a usual job being dangerous what we mean is that you're supposed to do A, but B might happen and hurt you (build the scaffolding for a house, but pinch your hand when connecting two pieces). Therefore we mandate PPE, maximum working hours, machine assurance, etc. This is possible because the actual job is tangential to the risk associated with it.

A clinical trial is, going from beginning to end: we have simulated this drug in the computer and tested it on cells. Now we need to check for interactions with other parts of the body. For statistically significant results we need 50 animals, we put cancer in them, wait two weeks and then start treating them like we would treat a human who has this cancer. We vary dose and when to give it, maybe the mixture of compounds if the drug is not just a single active component. A lot of the animals will have to be put down when it becomes apparent that this configuration of the drug does not work. But we have a better understanding of the working of the drug in the body now. After that trials move on to human patients. First we start with people who are sick and for whom the current method of treatment did not work. They will die soon anyway, but there is a small chance that the new drug will work on them. Again we vary dose etc, but now we know much better what range of dose is useful. This results in much more difficult to handle data, because taking a few random people will introduce wild variations in confounding factors. But it's a necessary step to show that the drug works in humans, because we can't move on to testing the new drug on people for which the old method of treatment would have worked. After this trial is done it is finally time to try the new drug out on people who come to the hospital to seek treatment. The doctor may offer you the chance to participate in a trial for a new medicine if they think you're a fitting candidate. This trial will test the medicine for the first time against a proper sample of the population. Only now can we say for certain how much better it is than the old drug (or maybe it's worse) and tease out details from the data (e.g. It's usually better, but it's worse if the person has a cold and is overweight when starting treatment. Or it causes severe allergic reactions for people who have asthma that is triggered by grass pollen)

It's important to note that at every step of the process a drug can fail testing. Researchers want the drug to fail early, because every step costs money and time. When we get better simulations or artificial organs to test on they will be used, because it's so much faster and cheaper than going to animal trials with a promising drug, only to find out after three months of hard work that it doesn't work.

Now, the safety concerns in clinical trials is that we have a current drug that works, and we have a new drug that may work. Is it ok to not treat someone with the known working one, just to see if the maybe working one helps? Most people say no. The danger is inherent in the thing, which is why we have such a lengthy process. There is no PPE you can wear to reduce the effects of cancer when the trial requires you to have cancer. We must get to the stage of "it's most likely working better than the current treatment" before starting testing on otherwise healthy humans.

[–] [email protected] 1 points 5 months ago* (last edited 5 months ago) (1 children)

Yeah, sorry for being vague. I'm not super knowledgeable about the field, just like if you asked me "how do we make deep sea welding safer?" I would maybe come up stuff like "put the welder in a shark cage" or "have them wear plated body armor so they don't get sucked in" or "make sure to train the diver really well and only go if they're feeling really well prepared/alert" but idk if those are actually the best way to make it safer, or whether they're already done.

Let me ask you this: are you opposed to professional fighting? Boxing, wrestling, wwe, etc? what about football or other sports where injury like concussion is common? That's a huge risk to health being done for money, and lots of poor folks are able to use those sports to get out of poverty. I don't think that's good, there should be nobody in poverty and the people doing sports should be doing so entirely voluntarily. Likewise my proposed bandaid to ending animal testing now is not ideal, but imo it would be just as valid as doing dangerous sports for money

And I do think a lot of people would be willing to try experimental medicine for their ailments voluntarily. It's fulfilling to be able to help contribute to humanities knowledge and help ratchet us forward, and being well compensated sweetens the deal even more

[–] [email protected] 2 points 5 months ago (1 children)

Fair enough. If you can recognize that you have a strong opinion based on ethics, and are willing to read up on how things are currently done and what the problems are (both with the current way and with the way that your ethics would like it to be) thats fine.

Let me ask you this: are you opposed to professional fighting? Boxing, wrestling, wwe, etc?

I'm not a sports guy (at least watching sports, I do exercise weekly) and would barely notice if those would no longer exist tomorrow. So I am certainly not one to defend their existence.
And yes, I am super critical of professional sport and how much these people hurt themselves. In German we have a saying: "Sport ist Mord", sports is murder. I think in the broad population it's also used as an excuse if you're lazy and don't want to exercise, but for me it appropriately hits on the problem of professional sport. Some are better than others, for example I have not heard of many negative consequences from swimming on a professional level. But I think the problems that people get from playing rugby on a professional level are absurd. There are measurable levels of IQ drop after a few years of working as an athlete. I have absolutely no idea why anyone would willingly do that.

One difference is that in order to get to such a level you need talent and need to be into it from a young age. Yes, some people can lift their family out of poverty with it. But not because they needed some quick money.
A better comparison to paying big money for participants of clinical trials than sports is selling your kidney. You only need one, technically, so it's safe on paper. But it's a surgery that comes with some inherent risks to your life. And there is a reason we usually have two.

And again, the injury is tangential to the performance. In clinical trials a sizable fraction of the "patients" die (cells, animals, humans. The earlier in the trial the bigger this fraction. Animal test are there to hopefully have the number be zero when we get to human trials), until we know what dose is effective and safe at the same time.

[–] [email protected] 1 points 5 months ago

Yep, I don't think the benefit we get from animal testing justifies exploiting animals like we do. I'd rather die because we don't know how to cure me than force any animals through what we do to them in testing, and I think it's selfish to say they should suffer for our gain. And to be clear there are aspects of my life where I act hypocritically there (e.g. crop deaths) but I'm working towards getting to a spot where I don't depend on that kind of thing, and if we as a species actually put our minds to it I think we could solve those problems so it didn't take such a tremendous amount of personal effort to stop contributing to it. But we need enough people to even recognize it's a problem worth solving first.

[–] [email protected] -1 points 5 months ago* (last edited 5 months ago) (1 children)

Halt all animal testing and put 100% of those freed up resources towards developing lab grown organs and tissues. If we want to study heart disease we should be growing human hearts and testing them, not using a "good enough" animal model. It could be the next big leap, like the Human Genome Project was.

[–] [email protected] 1 points 5 months ago

The problem with testing on organs or tissues is that you won't be able to see side-effects that affect unrelated organs. Maybe a stroke medicine increases the risk of internal bleeding or heart failure. Currently, medicines are tested on human tissue (HeLa lines - there's another sad story behind them, but I digress), and, if they pass, on mice. Only once they pass both are they even tested on humans.

[–] [email protected] 1 points 5 months ago
[–] [email protected] 1 points 5 months ago (1 children)

So, do you imply that as long as testing on animals is not cruel, it is ok?

[–] [email protected] 2 points 5 months ago (1 children)

The joke flew over your head. No animal testing is okay.

[–] [email protected] 0 points 5 months ago* (last edited 5 months ago)

Some carnists are so awful they can't even be satisfied with their almost complete hegemony. They have to come into our spaces to explain why we're actually dumb dumbs who changed huge portions of our lives and isolated ourselves socially without really thinking the basics through.

[–] [email protected] -1 points 5 months ago

If they find it, the hypocrites better use it on themselves as well.