Really the only thing I wish would go the hell away is item durability. It makes the rewards for things less cool. Like, oh look I did this long ass chain of fetch quests and got a beautiful sword that's a reference to a past game; better make the most of it before it fucking explodes. Get outta here with that.
I do wish the world was more open. I despise huge walls and climbing. Especially when explosives are abundant. We invented dynamite specifically to not have to deal with huge fucking cliffs everywhere; let's use some bomb flowers and really open shit up.