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Why ship pieces instead of shipping manufacturing capability (nano 3D printing etc) and use resources at the end point? By then presumably we've got asteroid mining down, no?
I think it would likely be similar to engineering materials today. The highest performing materials are very difficult to manufacture and we are talking about pushing them near their limits. I think a lot of the substructure will be made in-situ, but I think the most stressed parts of the main structure will require the largest scales of manufacturing. Like Sam Zeloof made a chip fab in a garage, so why doesn't he start producing the next Nvidia GPU. It is that kind of difference here. A lot can be done there, but nothing like what can be done on the cutting edge of what humans are capable of making at out largest and most advanced facilities.
Fair cop.