this post was submitted on 07 Nov 2023

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Seek relief (startrek.website)

submitted 1 year ago by [email protected] to c/[email protected]

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[–] [email protected] 76 points 1 year ago (4 children)

I rarely feel like it ever helps, and it's taxing on the kidneys/liver. So, I tend to not bother until it's bad enough.

[–] [email protected] 21 points 1 year ago (3 children)

My friend works out and takes pain meds frequently.

He also complains about yearly kidney stones.

I have never had a kidney stone. Where he's on his 8th one.

[–] [email protected] 16 points 1 year ago

Yeah, they're partly genetic but you can risk it. I have a couple of friends who have had their third or fourth stone and I've never felt so much as a slight discomfort on my kidneys. It makes me wonder wtf they're doing to themselves but I'm not one to judge.

[–] [email protected] 11 points 1 year ago* (last edited 1 year ago)

Was he on narcotics? I'm finding no link between Acetaminophen or Ibuprofen to kidney stones. Just drink more water.

https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-prevent-kidney-stones.html

https://pubmed.ncbi.nlm.nih.gov/30829133/

Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.

This appears to occur predominantly systemically in the liver [1,10], but may occur pre-systemically in the gut as well [11]. Ibuprofen is almost completely metabolized, with little to no unchanged drug found in the urine [1,9,12].

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/

Acetaminophen (APAP) is normally metabolized in the liver and kidney by P450 enzymes. No toxicity is observed with therapeutic doses of APAP.

https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys

https://pubmed.ncbi.nlm.nih.gov/8669426/

Tylenol (acetaminophen) is almost completely broken down by the liver. During this process, a toxic chemical forms. Normally, the liver makes it non-toxic. But if you take too much Tylenol, the liver can't properly process it all. The toxic chemical can then build up and poison liver cells.

https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys

[–] [email protected] 3 points 1 year ago

That was definitely the cause of my kidney stone, because I don't take OTC pain meds frequently, but if you do have ways to avoid kidney stones, avoid kidney stones. They are no fun.

[–] [email protected] 11 points 1 year ago

i'm the polar opposite, if i have a headache/migraine or cold symptoms i pop an ibuprofen and suddenly it's completely gone half an hour later.

[–] [email protected] 1 points 1 year ago (1 children)

Weird, because I can feel the Aspirin when I take it. It makes me feel ever so slightly numb all over and gummy at my core in a strange way. Kind of similar to when I eat a lot of sugar and it feels like I have syrup for blood and it leaves me lethargic.

[–] [email protected] 8 points 1 year ago (1 children)

Aspirin is a weird drug. Stick to ibuprofen or even just acetaminophen if you have stomach issues. Naproxen Sodium, Ibuprofen and Aspirin all irritate the stomach lining, and aspirin adds a risk of bleeding since it's also a blood thinner.

[–] [email protected] 4 points 1 year ago (1 children)

And acetaminophen is brutal on your liver if you take it often.

[–] [email protected] 1 points 1 year ago

And do not mix it with alcohol, that'll toast your liver in real short order.

[–] [email protected] 1 points 1 year ago

and it's taxing on the kidneys/liver

I hear you, I can only pretty much take acetaminophen... And yeah, it won't pay off well.