"Tautological denial of magic" seems like a total misunderstanding of the scientific method. If you know there's something "magical" you still can study it's effects on the real world.
Like someone here already commented, this is what we do in case of medical studies, "how good does this thing work compared to something that gives the illusion of working", the same can be done for whatever you define as your "magic".
It really isn't, malware still can easily break out as wine nor proton were never designed for isolation in the first place. Easy example is the Z drive giving program access to the whole Linux filesystem.