jpritikin73

joined 8 months ago
[–] [email protected] 1 points 1 month ago

After some self-experimentation, I'd say that CBN-O is 2-3x stronger than CBN. I'm not sure how long it lasts after ingestion (4-6 hours?), but its effects are mostly gone when I wake up. It's great stuff to aid sleep.

 

Since I enjoy cannabinol (CBN), I'm curious to learn about the acetylated version CBN-O. I've heard that CBN-O is stronger than CBN, but can anybody suggest anything more specific? Is CBN-O 10x stronger than CBN? What about duration? Is CBN-O more than 8 hour duration?

[–] [email protected] 1 points 4 months ago

I agree. I found Psychedelic experience dose-dependently modulated by cannabis: results of a prospective online survey that mentions, "cannabis smoked together with ayahuasca during ceremonies of the Brazilian Santo Daime Church." So I guess the combo is metabolically fine.

[–] [email protected] 0 points 4 months ago (2 children)

Thanks for your concern with my psychological state, but I'm just asking if there is metabolic a counter-indication like for mixing alcohol and opioids. Or the combo of warfarin and ibuprofen.

 

Any drug interaction that I should be worried about?

[–] [email protected] 1 points 7 months ago* (last edited 7 months ago)

Yep, I expect to post contradicting evidence soon. The current theory is that psilomethoxin is soluble in water but not methanol.

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submitted 8 months ago* (last edited 8 months ago) by [email protected] to c/[email protected]
 

Church of the Sacred Synthesis March 7 Press Release

The Church of the Sacred Synthesis (The Church) is pleased to announce that it has confirmed the presence of Psilomethoxin (4-HO-5-MeO-DMT) in its mushroom fruiting bodies.

These findings have been independently confirmed using triple quadrupole LC/MS instrumentation at the Chemical Purification, Analysis, and Screening Facility supervised by its director at the University of South Florida (USF) on Tuesday March 5, 2024.

The Church made the Psilomethoxin reference standard that it promised and will be able to test submitted sacramental Psilomethoxin contained in fruiting bodies provided by others who grow the sacrament on their own.

The Church has a distribution partner who will be making Psilomethoxin available over the counter (OTC) in a GMP formulation. We have a biotech partner who will be making Psilomethoxin OTC in a GMP formulation from yeast using gene editing. We have a university partner who will be conducting clinical trials on Psilomethoxin on the way towards an FDA indication.

The Church has sued Usona and others for defamation in Texas state court in Austin. The basis for our suit is that Usona is liable for their test of the anonymous unauthenticated sacrament due to the reckless disregard for the truth (actual malice) in the failure of their methodology to extract Psilomethoxin using methanol rather than water which Psilomethoxin is soluble in.

[–] [email protected] 2 points 8 months ago* (last edited 8 months ago)

Check out Santo Daime. When group behavior is the reference point, your conscious choice to harmonize with the group can help relieve varieties of self-centeredness including feeling entitled, lack of connection, and internal conflict. If your experience of psychedelics is only individual exploration then you have not had a chance to appreciate their full transformative potential.