It helps to contextualize this work in the movement it was part of: Dada. After the invention of photography the fine arts community was dealing with a crisis: painting was the primary form of art, and painting was meant to capture reality faithfully. Photography turns that on it's head and we get the beginnings of modern art with the Ashcan school in 1900 which makes everyday life, including the lives of the less fortunate, an acceptable subject of painting (previously it was nearly all portraiture, landscape and scenes from history or fiction).
Less representative paintings give way to abstract art, and just 19 years later we see that artists are pushing the bounds of what is considered "art". Duchamp and company were asking the question of "what is art" with each new piece and the overall movement of Data and it's descendants such as Fluxus has investigated that boundary for more than 100 years.
Yeah, and sure he can pass a drug test if you consider:
LSD: 12 hour wash-out time for a blood test
Cocaine: 24 hour wash-out time for a blood test
MDMA: 24-36 hour wash-out time for a blood test
Ketamine: 24 hour wash-out time for a blood test, and it's easy to get a prescription for off-label use to treat depression
So basically, do all the drugs you want Friday night, by Monday morning you'll be clean enough for a blood test.