In total 120 studies in 130 publications were included. Length of follow-up varied from 12 weeks to over 12 months. Few studies had low risk of bias. All complete and subgroup analyses except one had I2 ≥ 90%, with prevalence of persistent symptoms ranging between 0% and 93%. Studies using routine healthcare records tended to report lower prevalence of persistent symptoms/pathology than self-report. However, studies systematically investigating pathology in all participants at follow up tended to report the highest estimates of all three. Studies of hospitalised cases had generally higher estimates than community-based studies. Interpretation: The way in which Long Covid is defined and measured affects prevalence estimation. Given the widespread nature of SARSCoV2 infection globally, the burden of chronic illness is likely to be substantial even using the most conservative estimates.

Comparative genomics toolkit

Covid-19 has caused more than 1 million deaths in the US, including at least 1,204 deaths among children and young people (CYP) aged 0-19 years. Deaths among US CYP are rare in general, and so we argue here that the mortality burden of Covid-19 in CYP is best understood in the context of all other causes of CYP death. Using publicly available data from CDC WONDER on NCHS’s 113 Selected Causes of Death, and comparing to mortality in 2019, the immediate pre-pandemic period. Our findings underscore the public health relevance of Covid-19 to CYP. In the likely future context of sustained SARS-CoV-2 circulation, pharmaceutical and non-pharmaceutical interventions will continue to play an important role in limiting transmission of the virus in CYP and mitigating severe disease. #Academic #discussion

An article on reading scholarly articles.

This github repo contains lists of servers and users.

An interesting paper where the researchers conducted a cross sectional survey of people aged 18 years and above in Mexico. They divided people into two groups, one group who had toxoplasma infection in the past, and the other who did not, and for each group they measured their "attractiveness" (using other people) and also some parameters of "health" and "well being" and having good looks (such as "width of the face divided by height of the face", so the lower the value, the more attractive they are and so on), and for women measured their BMI. They found that those who had toxoplasma infection had "better looks" and scored high on "attractiveness" measures. If you read the paper, (free to read the full text), can you identify how many errors there are? What are they? Common sense, you do not need to be expert on anything on beauty or biology but if you are, even better. :-)

An interesting secondary analysis of different data sets. The paper compared how much households and government spends on healthcare in private and publicly funded health services in a state in India. The findings suggest that on an average, the spendings on private healthcare is three times that of public funded healthcare. The paper concluded that, "Using public resources for purchasing inpatient care services from private providers may not be a suitable strategy for such contexts."

Researchers studies 130, 000 records of individuals who were hospitalised or who died in the US. Then they studied the association between omicron strain and the deaths/hospitalisations after adjusting for the effects of vaccination but not treatment. The evidence is intuitive: omicron is as deadly as previous waves. What seems to happen is vaccines blunt the impact. This is a preprint

cross-posted from: https://lemmy.ml/post/63108

We are all in love with decentralized social topology, aren't we. But to make society reasonably decentralized, we need to remodel more than one level of it. I would like to bounce around some thoughts that may help establish a multilayer model of decentralized society.

::: Longwinded

1. Assumptions.

1.1. I use communications as an example of social activity that is a key to all other processes.

1.2. I assume that a decentralized network of heterogeneous communities is a good model for human society that we need now, as the all-crisis unfolds and neither democracy nor (even less) capitalism can offer any constructive approach.

1.3. I assume that the minimal provisions for an individual must include the right to participate in more than one community at the same time, the right to opt-out peacefully at any moment and the right to form a community (and participate in the network) on an equal basis.

2. Layers

2.1. "Fediverse". What we now see as fediverse is an implementation of communications pattern, where instances of various services can be associated with specific communities and their local users considered community members. Federation protocol provides a routine way to regulate interactions with other communities.

2.2. "Community Intranet". To control their collective memory, their policies/rituals and their boundaries, communities need to have control over the physical infrastructure of their "village intranet". It applies mostly to "natural" (local) communities, while "virtual" ones may need a trusted and neutral virtual hosting environment. The control should not, however, influence individual participation in remote communities.

2.3. "NetCommons". To keep the information flowing, society needs a non-owned, collectively managed transmission backbone. We can draw analogies with watershed management that is a known example of advantages and shortages of the commons approach.

2.4. "Platform Cooperatives". Economic (and, effectively, political) control of the means of production is a key to stability of the ecosystem. Thus, decentralized ecosystem of user cooperatives provides cohesion to the whole multilayered model. Every user becomes a member of the co-op(s) operating their community(ies) infrastructure. Community co-ops then form the "NetCoooperative", managing and maintaining the backbone systems and providing support, R&D and exception handling to communities in need.

3. Essential question is, whether such a model is comprehensive and complete enough to provide scaffolding for an attempt to implement proof-of-concept project.

Questions and comments welcome.

:::

This is a repost.

A tutorial on writing a peer review

A marker of sustainability.