StringTheory

This same relative also argued that cis men would go through transition just so they could be at the top of their sport (because they’d beat all the women) or so that they could get scholarships ear-marked for women (because they would be smarter than all the women and would win the scholarships). Somehow that seemed reasonable to them? How on earth!?!?

I got into a very strange argument with a relative (who doesn’t know any trans people -at least none they are aware of). They were absolutely convinced that ANY man is better than ALL women at all things. Athletic, intellectual, creative; men are inherently better at all of it.

Therefore, in their mind, anyone who was a man/boy at any point in their lives will be better at everything than a cis woman ever could be. So trans women will always dominate no matter what.

The profound misogyny at the base of their argument was flabbergasting.

Are you talking about internal hubs? There are many bikes with internal hubs available in the US, far more than bikes with Pinions. Even department/sports stores like REI sell bikes with internal hubs. I have 4 bikes with internal hubs, one is a CVT which is a hoot to shift but heavy as heck.

Good.

I worked in a fairly large clinic (office assistant type stuff) and always wondered why the top-surgery patients looked so much “better” than the mastectomy patients. Finally I asked one of the doctors, and he explained that top surgery is quite different than a mastectomy, with different protocols and goals and results.

Someone with training and experience performing mastectomies can’t just step in and do a top surgery.

Rental prices https://culdesac.com/tempe/apply/unit-selection/

So abused kids grow up to have smaller hippocampi, but not every person with a small hippocampus also has major depression?

I’m gonna be really shallow and judgmental and just say her picture is creepy, too. What a bizarre pose and expression.

Does the company that bought Osprey still honor the warranty?

Keen Newports have the finger loops on tongue and heel. I think Blundstone boots do, too? I’m sure someone with Blundstones can confirm or refute that.

Those loops are so handy, I agree.

Bicycle. No gas expenses, no tabs, no loan, free parking. I understand how it works and can mostly fix it myself for very little money. I can take quiet side streets and arrive in a much better mood, plus my fat lazy ass gets some exercise.

This is the cool part:

But histotripsy foils cancer’s cloaking efforts by destroying its cell walls, leaving the tumor antigens in plain sight for the body’s immune system.

This effect was detailed in a pair of papers published by the U-M research team between March 2022 and January 2023. They demonstrate that the sound waves used to break down cancerous tumors in rats also helped trigger the rats’ immune response. After histotripsy destroyed 50% to 75% of liver tumor volume, the rats’ immune systems cleared away the rest, with no evidence of recurrence or metastases in more than 80% of animals.

That immune response occurred throughout the body, not just in areas targeted by the histotripsy treatment, resulting in the reduction of tumors far from the treated area.

The immune response is key. Without it, histotripsy is just yet another way to destroy a tumor without curing the cancer.

There have been similar studies looking at “feeding” mannose to solid tumors. The starve-the-tumor-with-fake-nutrients option has a lot of potential.