I use reaper day in and day out for sound design and composition. It truly is more customizable and powerful than any other DAW in a few ways. That being said, Studio One smokes reaper in its weakest area…midi (e.g piano roll, expression maps , etc)
I still recommend Reaper because it’s so accessible and powerful. Just hope Cockos invest in midi feature like Cubase and Studio One have.
If I really think about it, what makes Mr. Or Ms. any easier to pronounce? They are actually a bit less intuitive because they are abbreviations.
As far as two letters go, I feel like Mx. is just one step removed from Mix, so it seems easy to me. Perhaps Mr. and Ms. are just easier to accept because we have lived with them our whole life. A lot of the English language seems weird when we step outside of it.