Vmware for mac is apparently accessible; it's the solution most blind folks use to virtualize Windows. However, I don't know about other platforms.
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There is a pretty robust command line for Virtualbox that lets you do most tasks. I'd recommend using that, though the learning curve will be much steeper, sorry. The hardest thing will be creating new images.
On Linux it's annoying because they use some outdated version of GTK so it also doesn't work with Orca either.