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the effects of psilocybin can be dampened by SSRI/SNRI for up to 3 months after cessation (pure.johnshopkins.edu)

submitted 3 months ago by [email protected] to c/[email protected]

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paper from Johns Hopkins. I wouldn't say the numbers are rock solid, but it's better than anecdotal

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[–] [email protected] 3 points 3 months ago (1 children)

Methods: Online retrospective survey of individuals with use of psilocybin mushrooms (1) with an antidepressant and/or (2) within 2 years of discontinuing an antidepressant. Participants who took mushrooms with an antidepressant and either took the same dose pre-antidepressant or took the same dose with other people not on antidepressant reported the strength of drug effects relative to their expectation. Participants who took mushrooms following discontinuation of an antidepressant also reported the presence of weakened effects.

Am I understanding the abstract here correctly - the only method used was an online survey?

[–] [email protected] 1 points 3 months ago (1 children)

Yes, that seems to be the case indeed.

[–] [email protected] 1 points 3 months ago

So it's BARELY better than anecdotal. (Literally a collection of anecdotes)