One of the funniest signs for me was when trying to design a VR game with a friend. For some background, it was a first person game where you can play pool remotely with others. With more of an emphasis on the social aspect than the game of pool. Didn't end up getting past the design phase though (yay ADHD).
At some point in our conversation, I brought up player character model - whether you should even have one, what is should look like, etc. I mentioned being able to select or change gender of this model, but he seemed a bit confused by that, and told me it would feel a bit wrong or uncomfortable in VR to look down at yourself and see a different gender. This confused the shit out of me, so I responded something like, "Really? I'd actually prefer looking down and seeing myself as a woman."
It would be another few years before my egg finally cracked.