There's a great podcast I started listening to before running it called Tabletop Gold which can really help you see how the adventure can play out, as well as some cool twists you can incorporate into the story. It's a delight to listen to as well.
I'd also recommend from my own experience working with your players to come up with backstory connections to the town of Otari and to the city of Absalom. The adventure is primarily set in Otari, and it features an existential threat to Absolom as the main driver of the plot. When I started the campaign, I told my players that they needed to include in their backstory some kind of personal connection to the city of Absolom, as well as a reason for why their character is in Otari.