Usually for Windows VM gaming you want to pass through a GPU and a USB controller and plug in directly. You might be able to use something like Steam streaming but I wouldn't recommend a normal desktop-app-oriented thin client setup, not having tried it.
You may run into weird problems with latency spikes: mostly it will work great and everything runs at 90 FPS or whatever, but then inexplicably 1 frame every few minutes takes 100ms and nobody can tell you why.
There can also be problems with storage access speed. What ought to be very fast storage on the host is substantially slower storage once the image file and host FS overhead, or the block device pass through overhead, come into play. Or maybe you just need an NVMe device to pass straight through.