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2024-11-11

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It’s time to admit that genes are not the blueprint for life (www.nature.com)

submitted 9 months ago* (last edited 9 months ago) by [email protected] to c/[email protected]

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Review of 2023 book: How Life Works: A User’s Guide to the New Biology Philip Ball. ISBN9781529095999

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[–] [email protected] 1 points 9 months ago (1 children)

A pretty deus ex machina approach.

How would the size of this plants genetic code be justified I wonder?

https://en.m.wikipedia.org/wiki/Paris_japonica

There are plenty of plants that execute the exact same functions with code thousands of times smaller.

To say every codon has a purpose is to be ignorant of how evolution works. There are start triplicate pairs and stop triplicate pairs, the regions between stop and start don't need to have function, even structurally, otherwise why would chromosomes come in different lengths? There was no creator of the genome, there was no efficiency driven outcome, there's only descent with modification, things just happen to with the way they work, and that's beautiful in it's own way.

[–] [email protected] 3 points 9 months ago

Again, and I can't emphasize this enough, this is not my area of study and seems like you have better handling of the subject. But when I read his quote, this part sticks out to me:

much of the exquisite control over these proteins is held offstage, nested within the noncoding junk.

Additionally, the article calls into question the role of code and protein production as the only role for DNA.

Still other noncoding stretches may be buffers against precipitous change, serving rather as flak jackets to absorb the impact of viruses and other genetic interlopers that infiltrate an animal's chromosomes. Without all the extra padding to absorb the blows, viruses or the bizarre genetic sequences that hop and skip from one part of the chromosome to another -- mysterious genetic elements called transposons or jumping genes -- might land smack in the middle of a crucial gene, disrupting its performance.

So there maybe stretches of DNA that don't participate in protein construction, but still has a role. So I question I idea of centering one type function over another.