I go against recommended practice and have different vaults for different things in my life. The academic note vault is separate from the personal vault is separate from the creative projects vault. I have also committed sacrilege by not having many notes linked to each other. I’m trying to migrate a lot of notes from Google Docs and Notion over into Obsidian, so all of the vaults are pretty messy.
I love the LaTeX integration. Lots of math formulas in the academic note vault. I use the callout feature everywhere. I also nest callouts in callouts. I’m frankly treating them as equivalent to toggles in Notion.
I most often go to the personal vault where I have a list of things I’ve 1) seen online before, 2) spent at least an hour trying to refind that thing later and 3) will probably want to find again. This way I don’t lose time trying to find it again. It’s really helpful for me. I also have a list of food brands and how much I liked them, so I can remember which brand of turkey was bad and which was tolerable and which I’d definitely buy again.
I use both Obsidian and Anytype right now. I find Anytype better for things like journal, networking, notes on the fly, habit and idea tracking, reading list, literature notes and so on.
I use obsidian as knowledge base for IT stuff and university notes. I also have a kanban because to keep track of what i learned and where to go next.
I also have another vault that i use for D&D, since i'm usually the DM i use Obsidian to world building, design campaigns, keep track of new ideas or requests from my player and what other players do.