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2024-11-11

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NHS scientists find new blood group solving 50-year mystery (www.bbc.com)

submitted 1 month ago by [email protected] to c/[email protected]

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The research team, led by NHS Blood and Transplant (NHSBT) scientists in South Gloucestershire and supported by the University of Bristol, found a blood group called MAL.

They identified the genetic background of the previously known AnWj blood group antigen, which was discovered in 1972 but unknown until now after this world-first test was developed.

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[–] [email protected] 9 points 1 month ago* (last edited 1 month ago)

These antigens are mainly significant in regards to blood transfusions.

People generally don't create antibodies against antigens that they have on their own cells.

If someone receives blood containing an antigen that isn't present on their own cells, and their body has already created antibodies against this "foregin" antigen, this can cause a hemolytic transfusion reaction (the transfused blood cells will rupture in the recipient), which can be fatal.