Science

3371 readers

517 users here now

General discussions about "science" itself

Be sure to also check out these other Fediverse science communities:

https://lemmy.ml/c/science

https://beehaw.org/c/science

founded 2 years ago

MODERATORS

[email protected]

154

Sleeping pills stop the brain’s system for cleaning out waste (arstechnica.com)

submitted 14 hours ago by [email protected] to c/[email protected]

22 comments fedilink hide all child comments

Her study found the glymphatic clearance was mediated by a hormone called norepinephrine and happened almost exclusively during the NREM sleep phase. But it only worked when sleep was natural. Anesthesia and sleeping pills shut this process down nearly completely.

you are viewing a single comment's thread
view the rest of the comments

[–] [email protected] 30 points 13 hours ago (3 children)

The study was only on zolpidem. IMO it can probably be generalised to other Z drugs, and possibly benzos. Drugs that work by entirely different mechanisms like melatonin and orexin antagonists could be completely different.

[–] [email protected] 4 points 12 hours ago (2 children)

What about Benadryl?

[–] [email protected] 17 points 11 hours ago

The hat man cleans your brain for you.

[–] [email protected] 4 points 11 hours ago

Unknown, but it's an anticholinergic, and those are associated with dementia.